Reed-Sternberg cells

Reed-Sternberg cells are large and are either multinucleated or have a bilobed nucleus (thus resembling an "owl's eye" appearance) with prominent eosinophilic inclusion-like nucleoli.The presence of these cells is necessary in the diagnosis of Hodgkin's lymphoma - absence of Reed-Sternberg cells has very high negative predictive value. They can also be found in reactive lymphadenopathy (such as infectious mononucleosis, carbamazepine associated lymphadenopathy) and very rarely non-Hodgkin lymphomas.

Esophageal Manometry

An esophageal motility study (EMS) or esophageal manometry is a test to assess motor function of the Upper Esophageal Sphincter (UES), Esophageal body and Lower Esophageal Sphincter (LES).

An EMS is typically done to evaluate suspected disorders of motility or peristalsis of the esophagus. These include achalasia, diffuse esophageal spasm, nutcracker esophagus and hypertensive lower esophageal sphincter. These disorders typically present with dysphagia, or difficulty swallowing, usually to both solids and liquids even initially. Other patients with spasm disorders may have the test done to diagnose chest pain thought not to be of cardiac cause. The test is not useful for anatomical disorders of the esophagus (that is, disorders that distort the anatomy of the esophagus), such as peptic strictures and esophageal cancer.

22nd workshopMicrosurgery of the Ear,12-13 February,2011,Gangaram Hospital ,Delhi

Course : 22nd Workshop of Microsurgery of the Ear

Date : 12th and 13th February,2011

Venue : Sir Ganga ram Hospital.

Contact : Dr Shalabh 09810121977
Registration fees for students is Rs1000/- and on spot registration is Rs1200/-
Delegates is Rs 1500/- and on spot registration is Rs2000/-
Cheque/DD to be sent in favour of " microsurgery of the Ear course" at following address
Dr.Shalabh Sharma
Vasant Vihar,
New Delhi-110057

There will be live interactive sessions on middle ear and mastoid surgeries, ossiculoplasties using prosthesis,BAHA surgery and facial nerve decompression and grafting.

Demonstration of temporal bone dissection and session of discussion on different aspects of middle ear and mastoind surgeries will also be held.

Temporal Bone Dissection course,March 5- 6,2011,Kurnool ,AP

2nd Hands on Temporal Bone Dissection Work Shop 2011
March - 5th & 6th 2011

Venue & Workshop Secretariat :
N.R.Peta, KURNOOL. Andra Pradesh
PH: 9440293940 ; 08518-224910.
Course Director : Dr.B. Jayaprakash Reddy

: Dr. Prahalad N.B, Banglore
Course Coordinators : Dr. Nadeem, Dr. Murali Krishna
Dr. Srinivas Kishore, Dr. Srinivasulu, Dr. Praveen
Fee Particulars
Post graduates
Rs. 3500/-
Rs. 5000/-

Limited seats first come first serve basis
Please pay after confirmation by course director
DD must be made in favor of
Kumar Reddy, Dr.Govindaraj

Life and Experiences of Dr. Paparella


OK-432: An effective sclerosing agent for the treatment of lymphangiomas of head and neck

OK-432: An effective sclerosing agent for the treatment of
lymphangiomas of head and neck
Baskota DK, Singh BB, Sinha BK
Assoc Professor, Department of ENT-Head & Neck Surgery, TU Teaching Hospital, Kathmandu.
FCPS Resident (II year), Department of ENT-Head & Neck Surgery, TU - Teaching Hospital,
Professor & Unit Chief, Department
of ENT - Head & Neck Surgery, TU Teaching Hospital
Objective: The basic objective of this study was to find out the efficacy of OK-432 for the conservative treatment of
lymphangiomas of head and neck regions at the Department of ENT-Head & Neck Surgery of Tribhuvan University
Teaching Hospital (TUTH), Kathmandu, Nepal.
Methods: It was a hospital based prospective, cross-sectional, case series, conducted among the patients suffering
from different lymphangiomas of head and neck regions and treated with intra-lesional injection of OK-432, from
March, 2005 to September 2006. Altogether eleven patients were enrolled in this modality of treatment out of which
one patient was excluded from the study, which was treated surgically due to very ugly scar at the site of lesion
resulting from previous surgery for the same. The data were analyzed by using simple mathematical tools like
percentage and frequency.
Results: Out of ten patients treated with intralesional injection of OK-432, absolute response, i.e. total resolution of
swelling was found in nine patients (90%) after the first dose. Remaining one patient also responded well on the
treatment but some residual swelling was in situ for which second dose was given. After the second dose it was also
totally resolved. In this way we achieved 100% response after the second dose of OK-432.
Conclusion: The results of this study so far indicate that OK-432 is an effective and safe tool for the treatment of
lymphangioma of head and neck region. As the procedure can be done in an out patient department, without
hospitalization and has got minimal side effects, it can be proposed as the first line treatment of lymphangiomas of
head and neck.
Key words: Lymphangioma, OK-432, Sclerotherapy, Sclerosing agent, Head and Neck

Photodynamic therapy of bacterial and fungal biofilm infections.

Methods Mol Biol. 2010;635:175-94.

Photodynamic therapy of bacterial and fungal biofilm infections.
Biel MA.

Virginia Piper Cancer Institute, Minneapolis, MN, USA.

Biofilms have been found to be involved in a wide variety of microbial infections in the body, by one estimate 80% of all infections. Infectious processes in which biofilms have been implicated include common problems such as urinary tract infections, catheter infections, middle-ear infections, sinusitis, formation of dental plaque, gingivitis, coating contact lenses, endocarditis, infections in cystic fibrosis, and infections of permanent indwelling devices such as joint prostheses and heart valves. Bacteria living in a biofilm usually have significantly different properties from free-floating bacteria of the same species, as the dense and protected environment of the film allows them to cooperate and interact in various ways. One benefit of this environment is increased resistance to detergents and antibiotics, as the dense extracellular matrix and the outer layer of cells protect the interior of the community. In some cases antibiotic resistance can be increased 1000-fold. Also, the biofilm bacteria excrete toxins that reversibly block important processes such as translation and protecting the cell from bactericidal antibiotics that are ineffective against inactive targets. In the head and neck area, biofilms are a major etiologic factor in periodontitis, wound infections, oral candidiasis, and sinus and ear infections. For the past several decades, photodynamic treatment has been reported in the literature to be effective in eradicating various microorganisms using different photosensitizers, different wavelengths of light, and different light sources. PDT has been further studied to demonstrate its effectiveness for the eradication of both Gram-negative and Gram-positive antibiotic-resistant bacteria. This chapter will focus on the use of PDT in the treatment of antibiotic-resistant biofilms, antibiotic-resistant wound infections, and azole-resistant oral candidiasis using methylene blue-based photodynamic therapy.

''Current Trends in Middle Ear and Sinus Surgey'' ,March 5,2011

Department of ENT, Padmashree Dr.D.Y.Patil Medical College announces one day workshop, ''Current Trends in Middle Ear and Sinus Surgey''

Live surgical demonstration by Dr. A.G.Pusalkar and Dr.Prabodh Karnik.
Workshop will have credit hours.

Contact Dr. Yogesh Dabholkar- 9920289334 for registration.


Isolated sphenoid sinus disease: differential diagnosis and management.

Isolated sphenoid sinus disease: differential diagnosis and management.
Ng YH, Sethi DS.

Department of Otolaryngology, Singapore General Hospital, Singapore.

PURPOSE OF REVIEW: To review the current literature on isolated disease of sphenoid sinus, and to describe the various approaches to the sphenoid sinus.

RECENT FINDINGS: Due to its posterior location and subtle presenting symptoms, sphenoid lesions, in the past, have often been missed and were reported as rare occurrences. However, with the availability of current diagnostic modalities such as endoscopy and imaging techniques such as computed tomography (CT) and magnetic resonance imaging (MRI), diseases of the sphenoid sinus are now more frequently diagnosed. Since the introduction of endoscopic techniques in the mid 1980s, various endoscopic approaches to the sphenoid sinus, depending on the extent and type of disease, have been described. These approaches were subsequently 'extended' to remove pituitary tumours, and certain diseases of the parasellar region and the petrous apex. More recently, further extension of these approaches has led to the development of endoscopic skull base surgery, using the sphenoid sinus as the 'gateway' to the anterior, middle and the posterior cranial fossa. These approaches require a clear understanding of the anatomy of the sphenoid sinus and its surrounding regions.

SUMMARY: This paper presents a review of the various diseases of the sphenoid sinus and describes the approaches to the sinus with special emphasis on the transpterygoid approach to the lateral recess of the sphenoid sinus.

17th Annual Conference on the Diseases of the Nose and Paranasal Sinuses,February 23 – 25, 2011 Semiramis InterContinental , Cairo - Egypt

Every year, we look forward to the Annual Rhinology Conference: the biggest rhinology event in the region that brings expertise and practitioners together in an atmosphere full of innovation and enterprise. In 2011, the main theme of the Conference is "The State of the Art in Endoscopic Sinonasal Surgery”.

It is our great honor to announce that the Egyptian Rhinology Group has won the bid for the IRS 2013 (International Rhinology Society) in addition to ISIAN 2013 [the International Symposium of Infection and Allergy of the Nose]. This prestigious annual conference is considered the biggest annual international Rhinology Gathering all over the world. It will be held in Sharm Al-Sheikh in October 2013 for the first time in the Middle East and/or Africa.

Moreover it will be a good chance to announce the establishment of the PARS (Pan Arab Rhinology Society). This society aims at enhancing the CME program in the field of Rhinology in the region.

Contact Us
For more information contact:
Reda Kamel, M.D.:
Professor of Rhinology, Cairo University
Tel.: 23802955 & 23632596
Fax: 27530124
Web site:

Office in Charge:
Conference Organizing Bureau
Dr.Shahenda El Hawary
14 El Khalil St., Lebanon Sq., Mohandessin, Giza, Egypt
Tel.: (202) 33023642 - 33027672
Fax: (202) 33027672
Web site :

11th International workshop On Rhinoplasty and cosmetic Facial surgery

Venue-Dubai -UAE

Under the Auspices of the Indian Society of Facial Plastic and reconstructive surgery and Akash Medical education foundation

Prof.Dr.Brajendra V.Baser

"New" Delhi Invites you to Phonocon 2011


CIGICON 2011,November 25-27,2011,Lucknow

We are organizing the 2011 CIGICON ( COCHLEAR IMPLANT ) workshop and national
conference from 25th to27th Nov. 2011. at Lucknow.
Dates - Cochlear implant workshop - 25th Nov.
Cochlear implant conference - 26,27th Nov.
Contact person - Dr. I. Tyagi.
Ph. 09838778776
Venue - Hotel Taj Lucknow

Senior ENT Consultant
Sahara Hospital
Formerly-Prof. Neurotology

Otology,Rhinology &Rhinoplasty Workshop,February 25-27,Bangalore

Venue: Basavanagudi ENT Centre
44/1,H.B. Samaja Road

Faculty : Dr A. Mahadevaiah
Dr H Vijayendra
Dr Vishnu Raddy

Contact : 26604569

E mail :

Fee : 2500/-
PG : 2000/-
DD Payable "Basanavagudi ENT Care Centre" payable at Bangalore

What is lymphoma?

Briefly, lymphomas result when DNA damage or changes occurs to an immune cell (a lymphocyte) that alters the behavior of the cells, leading to abnormal production of proteins that prevents the cells from dying when they should, or causes sustained rapid cell division that produces more of its kind. The malignant cells then may accumulate to form tumors that may enlarge the lymph nodes or spread to other areas of the lymphatic system, such as the spleen or bone marrow. Lymphoma can also spread or first appear outside the lymphatic system - so-called extranodal disease.

Endoscope-assisted intra-oral resection of the external thyroglossal duct cyst

Volume 32, Issue 1, Pages 71-74 (January 2011),American Journal of OHNMS
Yoon Kyoung So, MD, Jong In Jeong, MD, Hye-Youn Youm, MD, Han-Sin Jeong, MD, PhD
Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea

Endoscope-assisted intra-oral resection of the external thyroglossal duct cyst
Surgical removal of a thyroglossal duct cyst (TGDC) and its tract is usually accomplished through an external neck incision, including the removal of the middle part of hyoid bone and a block of tissues extending to the foramen cecum. However, this procedure inevitably results in neck scarring. We implemented a modified approach to TGDC removal in a 28-year-old woman through the floor of the mouth using an endoscope system.

Case report
Here, we describe the detailed procedure of the endoscope-assisted intra-oral resection for TGDC. The total operative time was 130 minutes. The patient complained of swelling and pain in the floor of the mouth for 2 days, but did not require any intervention. Follow-up imaging studies confirmed no recurrence (18 months) without any sequelae, and the patient was satisfied with her surgical outcome.

The intra-oral approach through the floor of the mouth is a technically feasible alternative surgical option that allows for complete removal of a TGDC without the neck scar.

Epiglottis is not essential for successful swallowing in humans.

Ann Otol Rhinol Laryngol. 2010 Dec;119(12):795-8.

Epiglottis is not essential for successful swallowing in humans.
Leder SB, Burrell MI, Van Daele DJ.

Department of Surgery, Section of Otolaryngology, Yale University School of Medicine, New Haven, Connecticut 06520-8041, USA.

Controversy has continued for well over 100 years regarding the role of the epiglottis in deglutition. We describe the effect of isolated epiglottectomy on swallowing success in a case series of 3 adult human subjects with isolated epiglottectomy due to trauma, surgery, or cancerous erosion. The patients were 42, 51, and 70 years of age, and swallowing was analyzed objectively with videofluoroscopy. All subjects exhibited successful swallowing with all food types: thin liquid, puree, and solid food. Specifically, the patient with traumatic epiglottectomy exhibited rapid swallowing success, the patient with surgical epiglottectomy exhibited a short period of dysphagia due to postoperative edema, followed by swallowing success, and the patient with epiglottectomy due to cancerous erosion of the entire epiglottis exhibited long-term adaptation, with successful swallowing maintained. We conclude that the epiglottis is not essential for successful swallowing in humans, because individuals can readily adapt to isolated epiglottectomy and avoid tracheal aspiration.

2nd International Airway Course & Hands on Cadaver, Tracheoplasty, Thyroplasty & Laser Training on 22nd , 23rd & 24th April 2011,Pune

The course is being organized by Department of Laryngology in Deenanath Mangeshkar Hospital at Pune, Maharashtra India.

Dr. Vasant Oswal, FRCS from UK is the course advisor. Prof. Luis Fernando Tintinago, MD from Colombia and Prof. Surendra Narne from Italy would be the International guest faculty along with some prominent Indian faculty.

The course includes Lectures, Live Surgical Demonstration by National & International Faculty, Case Discussion, Multipoint Video Conferencing, as well as hands-on cadaveric dissection, hands on laser course and hands on training on Simulators. 40 candidates would be enrolling for the Hands on Cadaveric Dissection.


With regards,

Dr. Sachin Gandhi
Course Director - Airway course 2011
Consultant ENT Surgeon & Director, Department of Laryngology
Deenanath Mangeshkar Hospital & Research Centre
Pune 411004 ,Maharashtra, India
Telephone: +91 (0)20 66023511 9595123008
Website :-

Workshop on Endoscopic DCR ,February 5,Nagpur

Time : Saturday, February 5 at 9:00am - February 6 at 5:00pm

Location: Orange City Hospita & Research Institute, Nagpur, India

Contact: Nandu Kolwadkar

More Info A workshop on Endoscopic DCR & Basic Steps in FESS is being organised at Orange City Hospital, Nagpur. Dr Milind Navalakhe, Dr Vaibhav Madane, Dr Virendra Ghaisas, Dr R B Deshmukh & Dr S Kothalkar are the operating faculties. This dedicated workshop would prove beneficial to the ENT consultants & PG's.

Contact for details : Dr Nandu Kolwadkar 9822396797 email: nandu44@gmail.

Update on Pedriatic Swallowing & Upper Airways,March 12-13,Hyderabad

Live microlaryngocopy and debate on decision make for each case.
Live surgery for neonatal , infant subglottic stenosis :cord palsy ,laryngomalacia(depending on case availability)
Live :functional endoscopic evaluation of swallowing(FEES)
Lectures based on scenario based management eg:new born stridor protocols.
OPPURTUNITY :to perform np scopy and functional endoscopic evaluation of swallowing on a dummy.
Dates :12 th and 13th March
Venue:TAJ Deccan Hotel Banjara hills
Contact person: PRATIMA ;
MOBILE:9177779185 email;

Info Dr Srinivas Kishore

Gujarat Society of Head & Neck Oncology,Fourth Annual Conference,Feb 19-20,Karamsad

Gujarat Society of Head & Neck Oncology

Fourth Annual Conference
February 19-20, 2011

H M Patel Academic Centre
Shree Krishna Hospital, Karamsad

Insructions for Abstract Submission
Dr. Siddharth Shah
Dept. of ENT and Head & Neck Surgery
Gokal Nagar, Karamsad - 388 325, Gujarat (India)
Ph: 91-2692-228133,228137 • Mob: 9726579818
Email: or

ENT PG Update 2011,Hyderabad,January 22-23,2011

The Association of Otolaryngologist of India
Andhra Pradesh State Branch

22nd & 23rd January 2011

Venue: Govt. ENT Hospital, Dr. A.B.N. Rao Conference Hall, Koti, Hyderabad.


Registration Form

Hony. Secretary
AOI AP State branch
Govt. ENT Hospital, Koti, Hyderabad -95.

"Ear & Sinus Surgery Workshop,Nashik, February 24-27 2011

"Ear & Sinus Surgery Workshop - 2011

Date : 24th & 27th February 2011.

Venue :Indorewala ENT Hospital, DNB Institute & Research Centre,
Behind Mahamarg Bus Stand, Old Mumbai Naka, Nasik-422 002

Contact Mr.Murtuza Modi, +9823154256

Guest Faculty: Dr.Prepageran Narayanan (Malaysia)
& Host Faculty is Dr.Shabbir Indorewala (Nashik).


First Successful Salivary Stone Removal With Robotics Reported By LSUHSC

Dr. Rohan Walvekar, Assistant Professor of Otolaryngology Head and Neck Surgery, Director of Clinical Research and the Salivary Endoscopy Service at LSU Health Sciences Center New Orleans, has reported the first use of a surgical robot guided by a miniature salivary endoscope to remove a 20mm salivary stone and repair the salivary duct of a 31-year-old patient. Giant stones have traditionally required complete removal of the salivary gland. Building upon their success with the combination of salivary endoscopic guidance with surgery, Dr. Walvekar and his team have significantly advanced the procedure by adding robotics. The technique not only saves the salivary gland, it also reduces blood loss, scarring, and hospital stay. The case is published online in the Early View (articles in advance of print) section of the journal, The Laryngoscope


International Visiting Scholarships for Indians--Policies

International Visiting Scholarships for Indians--Policies
To attend the AAO-HNSF Annual Meeting & OTO EXPO and participate in a short-term observership in a US academic department of otolaryngology.
Deadline for receipt of applications (email only)—close of business, May 1.

Program Overview
With the mission of Working for the Best Ear, Nose, and Throat Care, the Academy and Foundation’s international goal is to engage in high-quality interaction around the globe to ensure meaningful, diversified contributions to the specialty. This program is under the auspices of the AAO-HNSF Humanitarian Efforts Committee.

Launched in 2008, the intent of the International Visiting Scholar Program is to bring young academicians to the US from India (and other countries) to attend the AAO-HNSF Annual Meeting & OTO EXPO and take part in short-term observerships.

The International Visiting Scholarships for Indians are currently funded through 1) the American Association of Otolaryngologists of Indian Heritage, and 2) individual gifts from donors such as a) Dr. and Mrs. Vijay Anand and b) Dr. and Mrs. Dinesh Mehta.

For example, for $2,000, a scholarship for one year may be named for the donor, e.g., the Nikhil J. Bhatt International Visiting Scholar. For an endowment of $50,000 or more, a scholarship may be named in perpetuity.



If any queries, please contact

All good wishes,


Catherine R. Lincoln, CAE, MA (Oxon)
Senior Manager, International/Humanitarian
American Academy of Otolaryngology--Head and Neck Surgery
1650 Diagonal Road, Alexandria, VA 22314-2857, USA
Direct dial: 1-703-535-3738 Fax 1-703-299-1124;

Important Points about the New AAO-HNS Tonsillectomy Guideline

Important Points about the AAO-HNS Tonsillectomy Guideline
• Most children with frequent throat infection get better on their own;
watchful waiting is best for most children with <7 episodes in the past year, 5
per year in the past 2 years, or 3 per year in the past 3 years. Severe throat
infections are those with fever of >=101, swollen or tender neck glands,
coating on the tonsils, or a positive test for strep throat.
• Tonsillectomy can improve quality of life and reduce the frequency of severe
throat infection when there are at least 7 well-documented episodes in the past
year, 5 per year in the past 2 years, or 3 per year in the past 3 years.
• Children with less frequent or severe throat infections may still benefit
from tonsillectomy if there are modifying factors, including antibiotic
allergy/intolerance, a history of peritonsillar abscess, or PFAPA syndrome
(periodic fever, aphthous stomatitis, pharyngitis, and adenitis).
• Large tonsils can obstruct breathing at night, causing sleep-disordered
breathing (SDB), with snoring, mouth breathing, pauses in breathing, and
sometimes sleep apnoea. Physicians should ask parents of children with SDB and
large tonsils about problems that might improve after tonsillectomy, including
growth delay, poor school performance, bedwetting, and behavioural problems.
Although most children with SDB improve after tonsillectomy, some children,
especially those who are obese or have syndromes affecting the head and neck
may require further management.
• Physicians should give a single, intravenous dose of dexamethasone during
tonsillectomy to reduce pain, nausea, and vomiting after surgery.
• Physicians should not routinely prescribe antibiotics to improve recovery
following tonsillectomy surgery, because medical studies show no consistent
benefits over placebo and there are associated risks and side effects.
• Physicians should educate parents about the importance of managing and
reassessing pain after tonsillectomy. Strategies include drinking plenty of
fluids, using acetaminophen or ibuprofen for pain control, giving pain medicine
early and regularly, and encouraging their child to tell them if their throat
SOURCE: American Academy of Otolaryngology -- Head and Neck Surgery

Information Courtesy : Dr PP Devan


Conference : XXth Annual Conference of Indian Society of Otology

Dates : 11th ,12th and 13th of November2011

Venue : Amrita Institute of Medical Sciences ,Kochi.


Contact :Dr.Praveen Gopinath,Organising Secretary
Thankalayam,Nettoor P.O ,Ernakulam-682040
Phone- 0484-2700143, 859002774 , 9446140467

Email :

Welcome to AOICON 2011

This is to welcome you to the 63rd Annual Conf of AOI at Chennai from the 6th to 9th of January. Coming to the annual AOI conference is like a pilgrimage for all of us every year where we renew our bondage to the fraternity, pay respects to our teachers, meet friends and if time permits also update ourselves on the recent developments taking place in our discipline.

All this will be there in full measure in the upcoming 63rd AOICON also but this mother of all AOI conferences will offer a lot more to you. Expect the best but do not be surprised to experience something even better! All your senses will be stimulated to the hilt and you will savor an experience to preserve a lifetime. A very rich academic fare, a tantalising social program spiced with the best of South Indian hospitality will leave you charmed beyond expectation. The organizing team under the guidance of Dr Mohan and Dr Jacinth has left no stone unturned to ensure that you have a gala time at Chennai. If you can cook up a complaint or find a fault there will be a very special prize for you.

One small request; Please wake up in time to be there for the breakfast sessions and please be inside the halls while the scientific sessions are on. There will be plenty of attractions in the stands and outside the halls but all of us need to do justice to the efforts that go behind the scientific presentations by our colleagues and it is only your esteemed presence and your active participation that will provide the impetus to these scientific brains to carry the science of otolaryngology forward and evolve newer strategies for improving ENT health care.

Wishing all of you a very happy new year and eagerly waiting to see all of you at the 63rd ANNUAL CONFERENCE of AOI at CHENNAI

Dr Anirban Biswas

(President of AOI)