Dual disease -CLL +SCC

Chronic lymphocytic leukaemia in the right half of the field, and fibrous tissue containing squamous cell carcinoma in the left (haematoxylin and eosin, original magnification ×200).

Authors describe a case in which ultrasound-guided fine needle core biopsy of a cervical lymph node enabled diagnosis of dual disease. Histological examination of the core biopsy confirmed unsuspected chronic lymphocytic leukaemia with an isolated focus of metastatic squamous cell carcinoma (SCC), and enabled optimal preoperative planning of treatment. Such a case is extremely unusual and provides evidence of the accurate diagnosis that can be obtained from nodal investigations using ultrasound-guided core biopsy.